Postdoctoral Research Fellow

Sylvester Comprehensive Cancer Center-University of Miami Health System
According to NIH guidelines
June 29 2016
Position Type
Full Time
Job Type
PhD Fellowship

A postdoctoral research fellow position is available immediately in Professor Jonathan Trent’s laboratory at the Sylvester Comprehensive Cancer Center/University of Miami. The projects are focused on examining the role of the Wnt pathway in sarcoma pathogenesis and progression. The studies involve elucidating the basic mechanisms of Wnt epigenetic deregulation and crosstalk with other stem cell pathways in mesenchymal tumors, using in vitro and preclinical in vivo models. 
    The successful candidate will work under the supervision of Dr. J. Eid with the goal to develop the research described in the publication:
Targeting the Wnt pathway in synovial sarcoma models.
Barham W, Frump AL, Sherrill TP, Garcia CB, Saito-Diaz K, VanSaun MN, Fingleton B, Gleaves L, Orton D, Capecchi MR, Blackwell TS, Lee E, Yull F, Eid JE. Cancer Discov. 2013 Nov;3(11):1286-301. 
    This research involves projects related to understanding cancer stem cell signaling and epigenetics using the latest techniques in basic cancer biology and high throughput analyses (ChIP-seq, RNA-seq), as well as developing preclinical mouse models and drug treatments.

The qualifications for this position are as follows:
We are looking for a highly driven, passionate candidate with a strong interest in high quality research and in making basic discoveries to help with the cure for cancer. The successful candidate should have:
• A PhD in Life Sciences, preferably cancer biology
• An established track record of publication in peer-reviewed scientific journals
• Training in signal transduction, stem cell and/or cancer biology
• Excellent written and oral communication skills, fluency in English is essential
• A natural ability to work within an interactive team of scientists

Interested, creative candidates should send a cover letter describing their research experience and interests, a CV, and names and addresses of 3 references to