A NIH-funded postdoctoral position is available in Dr. Stephanie Karst’s lab at the University of Florida College of Medicine to study the interplay between noroviruses and the intestinal microbiota. We recently discovered that commensal bacteria control the intestinal regional preference of norovirus infection. Moreover, human norovirus infection of B cells requires a commensal bacterial co-factor [Science 2014, 346(6210):755-9; Nat Protoc 2015, 10(12):1939-47]. These data are consistent with a growing body of evidence that commensal bacteria play an absolutely critical role in regulating viral infections in the gut [Nat Rev Microbiol 2016, 14(4):197-204]. This emerging area of research is extremely exciting and undoubtedly impacts not only viral replication along the intestinal tract but also virulence, cell tropism and antiviral immunity. We are seeking a highly motivated postdoc to probe the influence of commensal bacteria on norovirus immune responses. Candidates with a strong background in animal models and immunology are especially encouraged to apply.
The Karst laboratory is affiliated with the Department of Molecular Genetics & Microbiology, the Emerging Pathogens Institute, and the Center for Inflammation & Mucosal Immunology at University of Florida, providing an excellent environment for postdoctoral training. Our Department has an exceptionally strong and interactive virology group.
Interested applicants may send their resume and contact information for three references to Dr. Stephanie Karst at: email@example.com