PhD Student in the area of cancer metabolism

Employer
German Cancer Research Center
Location
Germany
Posted
April 22 2016
Position Type
Full Time
The German Cancer Research Center (DKFZ) in Heidelberg, Germany, invites application for a highly motivated and creative PhD student to explore the molecular bases underlying metabolic reprogramming in cancer.



Cancer cells display profound metabolic alterations that enable them to meet the metabolic needs required for various aspects of malignancy. Understanding this metabolic remodeling is essential to decipher the fundamental mechanisms of tumorgenesis, as well as to find novel therapeutic solutions. Iron is a trace element important for many cellular functions and like other metabolic pathways, iron homeostatic mechanisms are frequently altered in cancer (Torti and Torti, Nat. Rev. Cancer, 2013).



In this project, we will make use of state-of-the-art tumor mouse models together with organoid cultures and various cell and molecular biology approaches to investigate the role of central regulatory networks of iron homeostasis in tumor biology, with a particular interest for intestinal cancers.



Your profile:

Applicants should hold a masters' degree (or equivalent) in biology, biochemistry or related field, with an excellent background in tumor biology and a strong experience in cell and molecular biology techniques; experience in mouse models would be advantageous. The student shall be committed, enthusiastic, rigorous and goal oriented. The candidate shall be very well organized, have excellent communication and writing skills, and be able to work both independently and in a team environment.



Please send your CV, copies of certificates, transcript of records from Bachelor's and Master's studies, your research interests and contact addresses of two referees.



The position is limited to 3 years.



For further information please contact

Dr. Bruno Galy, phone 06221 42-4979.



The German Cancer Research Center is committed to increase the percentage of female scientists and encourages female applicants to apply. Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.



To apply for a position please use our online application portal (www.dkfz.de/jobs).



We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personal- und Sozialwesen, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.

This job comes from a partnership with Science Magazine and Euraxess

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