Universitat Pompeu Fabra
April 12 2016
Position Type
Full Time
We are searching for highly motivated postdocs with expertise in Genetics, Epigenetics, Molecular and Cell Biology, with a strong peer-reviewed publication record and professional references. The successful candidates will be expected to design and carry out experiments to test the biological relevance of candidate driver mutations derived from computational studies currently under way in the group. They are expected to work independently and collaboratively, primarily using human cell lines and ex vivo models, as needed to advance the project. Specific duties will include: cellular transgenesis and genome editing with the use of CRISPR/Cas9 technology; functional and biochemical essays; drug sensitivity tests; development and interpretation of high-throughput screening methods; and manuscript preparation in cooperation with the P.I. Eventually, the successful candidates will be responsible for training other junior laboratory personnel, as needed.

Position requirements:

- A Ph.D. in the field of molecular biology, biochemistry, cell biology, cancer biology, genetics or related field.

- At least 3 years of postdoctoral experience.

- Candidates should have the ability to work independently and within a collaborative research team, and possess excellent communication and organisation skills.

- Experience in genome editing technologies, cancer genomics, cell culture and high-throughput screening will be appreciated.

The group leaded by Nuria Lopez-Bigas is a strong interdisciplinary and international research team currently formed by 4 postdocs, 2 PhD students and 2 software engineers, with complementary expertise in biology, medicine, computational biology and software engineering. The research team has unique expertise in the analysis of tumour genomics data. Recent achievements include (see publications in i) genome-wide identification of cancer drivers, ii) participation in the most important international consortia in cancer genomics (ICGC and TCGA), iii) discovery that protein-bound DNA impairs nucleotide excision repair.

This job comes from a partnership with Science Magazine and Euraxess