PhD position in high resolution analysis of shuttling proteins during stem cell differentiation

St. Anne's University Hospital Brno
Czech Republic
March 24 2016
Position Type
Full Time
We seek a highly motivated individual to join an EU-funded project within the Center for Translational Medicine (CTM), International Clinical Research Center (FNUSA-ICRC). The working activities involve the culture and differentiation of adult and pluripotent stem cells, the analysis of gene and protein expression, the exploitation of high resolution and super-resolution microscopy to investigate the localization of mechanosensor proteins. The activities also include gain and loss-of-function experiments and live confocal microscopy imaging.

ICRC is a joint research centre of St. Anne´s University Hospital in Brno and Mayo Clinic in Rochester, Minnesota (USA) and links together pre-clinical basic research (e.g. in stem cell biology, cancer biology etc.) with clinical research (for more info see Formerly known as Integrated Center for Cell Therapy and Regenerative Medicine (ICCT), CTM is headed by Dr. Giancarlo Forte and develops basic and pre-clinical research in the field of aging-related diseases ( The advertised position is meant for a post-graduate student in the early stage of his/her career.



- completion of Master Degree in Biological Sciences, Biotechnology, Industrial Biotechnology or similar.

- good knowledge of cellular biology and at least basic understanding of the mechanotransduction processes.

- familiarity with stem cell culture is a plus.

- interest in developing a solid, competitive research program in stem cell mechanobiology.

Prerequisites for successful role performance

The applicant should have the will to acquire a strong expertise in adult and pluripotent stem cell biology and to apply interdisciplinary approaches to pursue the goal.

Being already familiar with cell-cell, cell-ECM interaction/communication and/or protein-protein interaction would represent a benefit.

The specific requirements on the applicant are as follows:

- Previous experience with cell culture, methods of molecular biology, and advanced microscopy

- Good level of communication in English language (verbal and written)

- Computer ability (MS office, image analysis)

Professional requirements:

• Ability to comply with laboratory rules

• Ability to team-play in an international context

Personal characteristics:

Successful candidates should be highly motivated and curious, demonstrate the ability to develop independent thinking, and be prepared to work in a highly competitive environment.

This job comes from a partnership with Science Magazine and Euraxess

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