Ai Lab is in Newborn Developmental Biology Laboratories, Department of Pediatrics at Mass General Hospital, Harvard Medical School. As a developmental biologist, Dr. Ai studies lung diseases in young children. One of Dr. Ai's major interests is the development of the nervous system in the lung and how age-related neural communication with airway smooth muscle cells, pulmonary neuroendocrine cells, and immune cells contributes to pathogenesis of childhood diseases, including allergic asthma and sudden infant death syndrome. The second major project in Dr. Ai's laboratory is to investigate pathogenesis of lung defects caused by congenital conditions, prematurity, and respiratory viral infection in infants. The second project leverages Dr. Ai's ability to derive airway basal stem cells and mesenchymal progenitors from tracheal aspirates of newborns. Dr. Ai's lab is located on the Charles River campus of MGH and offers dynamic and exciting opportunities for career development.