NIH-funded postdoctoral position

Location
University of Oklahoma Health Sciences Center, Oklahoma City, USA
Salary
in accordance with NIH minimum stipend plus benefits
Posted
February 21 2019
Position Type
Full Time
Organization Type
Academia
Job Type
Postdoc

Postdoc position on Diabetes, Obesity, and Cardiac Function at OUHSC

Job Description

An NIH funded postdoctoral position is available immediately in the laboratories of Drs. Hui-Ying Lim and Weidong Wang at the University of Oklahoma Health Sciences Center (OUHSC). We are seeking a highly motivated postdoctoral scholar to pursue high quality research in one or more of the following areas:

Cellular and Molecular biology in Diabetes and Metabolism. The candidate will study the roles of several novel genes and chemicals we recently identified in pancreatic beta cell biology, insulin action, insulin resistance, and other aspects in the pathogenesis of diabetes.

Cellular and Molecular biology in Cardiac Function. The candidate will study the physiological roles of reactive oxygen species signaling on heart function and development using a combination of cell biology, molecular biology and imaging techniques, in both fly and mouse models.

Molecular and cellular biology and biochemical techniques as well as transgenic/knockout mouse and fly models will be utilized for the above studies. A Ph.D. in Biochemistry, Molecular and Cell Biology, Physiology, Pharmacology or related field is required. Strong expertise in molecular and cellular biology, protein biochemistry, or experience with animal models of diabetes or of metabolic disorders is preferred.

Medicinal /bioorganic chemistry or chemical biology: another direction of our research is at the interface of biology and chemistry, for the discovery and development of drugs for treatment of diabetes. We discover and study small molecules that promote pancreatic insulin-producing beta cell differentiation from stem cells, and beta cell regeneration and survival using biochemical or cell-based high throughput screening technology. The candidate for this position will be responsible for the design and/or synthesis of analogs of hit compounds, and SAR studies. A Ph.D. in bioorganic chemistry, medicinal chemistry, chemical biology, or related fields with experiences in synthetic organic chemistry is required. Knowledge in biology or experience in cell culture and any biology experiment is a plus, but not required.

Our group is committed to training postdoctoral fellows for scientific career advancement, including the provision of unique opportunities to learn a broad range of techniques and collaborative projects involving fly and mouse models. Candidates must be self-driven, highly motivated and well organized. Must be able to multi-task and solve problems creatively, with the ability to work independently as well as cooperatively with a team. Excellent oral and written communication skills are required.  Candidates with fresh Ph.D. or within 1 year of post-doctoral experience and first-author publications in internationally recognized journals are preferred.  

Interested candidates should send a letter that describes your scientific interest and research experience, together with your CV, list of publications and the names of three references to Dr. Weidong Wang at weidong-wang@ouhsc.edu and huiying-lim@ouhsc.edu. Please also visit our websites http://www.ouhsc.edu/endocrinology/faculty/Wang.asp and https://www.oumedicine.com/physiology/department-information/faculty/hui-ying-lim for more information about our research.

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