Scientist III, BioProcess R&D - Process Development
When you join us at Thermo Fisher Scientific, you'll be part of a smart, driven team that shares your passion for exploration and discovery. With revenues of $17 billion and the largest investment in R&D in the industry, we give our people the resources and opportunities to make significant contributions to the world.
We are searching for a Bioprocess Research Scientist that will drive product innovation through adaption of existing technology; along with innovate via conceptualization, research, design, and evaluation. This role will work directly within Thermo Fisher to support research and commercialization of bio-manufacturing techniques used to create cell based drug therapies (e.g. Mesenchymal Stem Cell Therapy or T Cell Therapy).
- Lead technical initiatives, conduct and oversee studies using cutting edge analytics (LC-MS, GC-MS, ICP-MS, UHPLC, Raman, and similar quantitative methods). This includes performing extractable studies of single-use films and components
- Serve as in-house technical expert in the field of applied sciences. Providing technical leadership in the areas of biocompatible materials, process characterization, and biotheraputic stability under various process or storage conditions.
- Provide expert vision and strategy for aligning to industry standards and protocols related to discovery, manufacture, formulation, efficacy, storage, handling and safety pharmaceuticals and vaccines (BPOG, BPSA, ASME-BE, ASTM, ISO, ISTA, USP, WHO, ICH, FDA, EMA, GMP, ect)
- Perform extractable studies of single-use films and components
- Independently design robust experimental plans, conduct and oversee studies, and analyze and report study results and recommendations both verbally and in written formats.
- Perform or support analysis and modeling of components and/or systems (i.e. heat and mass transfer, CFD, surface chemistry, biological networks etc.)
- Supports technology transfer into development
- Lead in process feasibility, characterization, automation, and validation studies as needed.
- Document experimental results/concepts to support patent and intellectual property portfolio
- Compile findings into documents ready for publication in academic or trade journals
- Interact with customer base on new product and process concepts including alpha and beta testing
- Present at technical conferences and represent the company as a thought leader in industry
- Travel as required to perform job functions.
- Bachelor's of Science Degree in related field - chemistry, physics, material science, biotechnology or chemical engineering.
- Bachelor's degree, with 5 years of experience, or Advanced degree with 3 years of experience
Following skills desired:
- Knowledge of bioprocessing operations (suspension cell culture, adherent cell culture, harvest & recovery) and cGMP/GLP (Current Good Manufacturing/Lab Practices) type environments.
- Strong knowledge of cell biology and/or biochemistry, especially with respect to interaction with biopharmaceutical processes and process equipment
- Experience in the medical device or biopharmaceutical industries.
- Experience and knowledge of analytical instrumentation (eg - HPLC, GC-MS, LC/MS).
- Software proficiency: MS office programs, Xcalibur, Chromeleon, DeltaV, SAS/JMP, DoE, Matlab/simulink, Visio
- Proficient in scientific method/analysis and applied mathematics/statistics.
- Ability to deconstruct technology concepts into core principles and determine feasibility for product development
- Team oriented with excellent written and oral communication skills
- Project management skills, time management discipline, Gantt charting
- Experience directing technicians for maximum resource utilization
Non-Negotiable Hiring Criteria:
- College engineering or science degree in applicable technical field.
- Advanced degree or BS w/ +5 years of relevant experience
- Laboratory research or process development experience.
- Strong written and oral communication skills.
- Ability to learn quickly, work independently and in groups
- Position may include travel up to 15%
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.