PhD candidate School for Mental Health and Neuroscience / department of Radiology
The position is embedded in the School for Mental Health and Neuroscience in Maastricht. Pathology of small vessels is known to contribute to many brain diseases, including dementia and vascular cognitive impairment. With the candidates work we aim to visualize the interaction between small vessels, brain tissue and declining function, and in particular the relation with hypertension. For this, novel functional and morphological vascular MRI techniques need to be advanced to detect abnormalities of the cerebral microcirculation. Important methods for this approach will be the measurement of dynamic blood flow fluctuations and leakage of the blood-brain barrier using 7.0 Tesla MRI. The challenge will be the development and evaluation of novel vascular techniques at ultra-high-field. As a PhD-student with a technical background, your main focus will be on all aspects pertaining to MR image acquisition, computational modeling, and data analysis. You will closely collaborate with a PhD-student with a clinical background, MRI scientists, and physicians.
You are a highly motivated technological innovator with a team spirit. Preferably, you have affinity with clinical and/or basic scientific research, are able to work in a multidisciplinary setting, you like complex and quantitative problems, and have good skills in English. To communicate with patients and hospital employees, experience with the Dutch language is advised. A M.Sc. degree is required in physics, chemistry, electrical engineering, biomedical engineering, computer science, neurosciences, biology, or other related fields of study. Experience with MRI, data analysis, and Matlab programming is a strong advantage.
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