Postdoctoral Research in Cancer Biology Laboratory
A postdoctoral position is available in the laboratory of Dr. Lewis Chodosh in the Department of Cancer Biology and Abramson Family Cancer Research Institute at the Perelman School of Medicine at the University of Pennsylvania. The candidate will lead multidisciplinary projects aimed at understanding the biology of tumor dormancy and recurrence.
The Chodosh laboratory uses genetically engineered mouse models, patient samples and computational biology to study the mechanisms by which breast cancers develop, become resistant to therapy, and ultimately contribute to cancer mortality. A broad array of basic and translational research approaches are used to address problems of fundamental clinical importance to cancer patients by elucidating pathways and principles common to human cancers. Particular areas of interest include: pathways regulating cancer development, metastasis, tumor dormancy and recurrence; the use of genomics and computational approaches to understand genetic programs in cancer; the impact of obesity on cancer recurrence; the mechanisms by which pregnancy protects against breast cancer; the role of the Hunk protein kinase in oncogenesis; and the use of non-invasive imaging approaches to study tumor biology. These approaches employ molecular, cellular, animal, human, and in silico model systems to study the function of key regulatory molecules in tumor biology using genetics, genomics, molecular biology, biochemistry, cell biology, computational biology, functional imaging, animal studies, preclinical trials and clinical investigation.
We seek highly qualified individuals who are highly motivated, flexible, collaborative, detail-oriented, and have the ability to multitask and a commitment to research excellence. The successful candidate should have a PhD and/or MD degree with a strong background in molecular biology, cell biology, genomics, and/or biochemistry. Research experience in flow cytometry and animal models would be advantageous.
Please forward a cover letter, CV, and the names/addresses of 3 references to:
Lewis A. Chodosh, M.D., Ph.D.
Professor and Chairman, Department of Cancer Biology
Associate Director for Basic Science, Abramson Cancer Center
Perelman School of Medicine
University of Pennsylvania
614 BRB II/III
421 Curie Boulevard
Philadelphia, PA 19104-6160