Senior Research Associate | Deputy Lab Head
Join Austria’s first research institute dedicated to the biological basis and molecular therapy of rare and undiagnosed diseases!
More than 7,000 rare diseases exist and affect around 5% of the population, constituting a major unmet medical need. Rare and undiagnosed diseases also offer unique opportunities to identify key genes and mechanisms underlying human physiology and disease. Many are caused by single-gene defects, thus enabling a clear mechanistic understanding of genotype-phenotype links relevant in humans and to develop concepts for personalized therapy. Rare and undiagnosed diseases are paradigmatic for the era of precision medicine, and the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD) broadly embraces their pioneering role for the future of medicine.
We are looking for an outstanding biomedical scientist/medical doctor to join the director’s group as
Senior Research Associate/Deputy Lab Head
Together with the Lab Head and Director of LBI-RUD, Kaan Boztug, you will be responsible for the coordination and advancement of the group’s research projects.
The research focus of our group is on the identification of rare monogenic disorders of the immune system and hematopoiesis to explain pathophysiological manifestations in humans (Salzer E et al Nat Immunol 2016, Dobbs K et al NEJM 2015, Boztug K at al Nat Genet 2014, Willmann K et al Nat Commun 2014). In the context of this work, we apply a combination of state-of-the-art genetic and genomic technologies incl. next generation sequencing, and a wide range of cellular and molecular techniques to elucidate novel pathways important for immune system homeostasis.
The group works in a fully equipped molecular biology laboratory in a shared environment with cell culture, multi-color flow cytometry as well as all equipment needed for state-of-the-art genomic investigations such as SNP arrays and deep sequencing, which are immediately accessible in-house.
This challenging multifaceted position requires a highly dedicated and motivated person who will substantially contribute to:
- the ongoing research projects focusing on (i) autoimmune and autoinflammatory diseases incl. inflammatory bowel disease and SLE-like syndromes, (ii) diseases of the adaptive immune system, i.e. (severe) combined immunodeficiencies, and (iii) diseases of the myeloid lineage through wetlab work and supervision of scientific staff with the possibility of first and contributing authorships on scientific publications
- knowledge dissemination and fundraising activities through writing of research publications and third-party funding proposals
- administrative support to the research projects through writing of ethics proposals and periodic reporting to funding bodies and agencies
- optimization of genetics and genomics pipelines in the lab through organization of standard operating procedures for genetic testing, interaction with clinical partners, overlooking patient sample and clinical data organization
- keeping track of advances in the NGS-based technology field for identification of primary immunodeficiencies
- keeping track of the newest research literature in the field of primary immunodeficiencies and participating in regular lab and institute meetings and journal club series
Requirements and Qualifications
You have experience in directing and supervising research staff (senior postdoc level), are exceptionally well organized, efficient and have excellent oral and written communication skills in English (knowledge of German is a plus). You are a proactive and independent scientist with a strong scientific track record in Immunology, Genetics, Medicine or Molecular Biology obtained through postdoctoral training, as evidenced by scientific publications in high impact factor journals and others. In addition, you have an excellent work ethic and outstanding interpersonal skills. You are able to connect different scientific disciplines, and have a keen affection to scientific project management.
About the Institute
The newly founded Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD) is directed by Kaan Boztug, a world-leading expert in primary immunodeficiency research. We are situated in a beautiful, bright, and perfectly designed building with outstanding design and state-of-the-art laboratories and technology platforms and are strategically located next to one of the world’s largest university hospitals in the heart of the city. The institute is deeply integrated with its renowned partner institutions, namely the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, the Medical University of Vienna, and the Children’s Cancer Research Institute of the St. Anna Children’s Hospital, and, therefore perfectly situated to benefit from strong translational research long established by leading-edge research groups.
Applications should be in English and should contain the following information: cover letter, CV, publication and – if applicable – funding track record, and names and contact details of three referees. Please summarize in one paragraph (max ½ page) what you believe is your single greatest research or technical development achievement to date and why.
Please submit your application in a single PDF file to: email@example.com using the reference code #SRA/KB17 in the header.
30th of April 2017 (call will remain open until the position is filled)
You should have an exceptionally high level of energy and drive, an excellent work ethic and very good communication skills. Salary and conditions are commensurate with experience according to FWF salary schemes (http://www.fwf.ac.at/en/research-funding/personnel-costs)
For more information please visit the LBI-RUD website: www.rare-diseases.at
Commitment to Diversity
We believe that diversity and a multicultural work environment are clear advantages for successful research and are therefore committed to attract, develop, and advance the most talented individuals regardless of their gender, race, sexual orientation, religion, age, disability status or any other dimension of diversity. We are happy to provide help and assistance to all our employees, their spouses and family members in terms of visa and relocation procedures, dual-career and childcare services, and others.