Principal Investigator - Rare and Undiagnosed Diseases
Join Austria’s new research institute for rare and undiagnosed diseases research!
at the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD) in Vienna, Austria
We are looking for an outstanding biomedical scientist to start or consolidate her/his research group at an exciting new institute pursuing basic and translational research on rare genetic diseases. Relevant areas include (but are not limited to) the hematopoietic and immune system as well as the nervous system. Systems biology approaches are equally appreciated as focused mechanistic studies and translational research with direct clinical applications, or any combination of the above. While the institute’s focus is on human diseases, animal models have a well-established role in rare diseases research and could be a relevant contribution.
More than 7,000 rare diseases together affect around 5% of the population, constituting a major unmet medical need. Rare and undiagnosed diseases offer unique research opportunities to identify key genes and mechanisms relevant to human physiology and diseases. Many rare diseases are caused by single-gene defects, thus enabling dissection of fundamental mechanistic principles with broad relevance beyond the disease that led to their discovery. Rare and undiagnosed diseases are paradigmatic for the era of precision medicine, and LBI-RUD embraces their pioneering role for the future of medicine.
LBI-RUD was launched with an ambitious research program on the genetic and epigenetic origin and the functional basis of rare diseases, with a special focus on inborn errors of immunity and hematopoiesis and the nervous system. Recent scientific publications by LBI-RUD principal investigators have enabled the identification of novel genetic defects underlying immunodeficiency disorders and monogenic neuronal diseases (Boztug K et al. Nat Genet 2014, Dobbs K et al. New Engl J Med 2015, Salzer E et al. Nat Immunol 2016, Nagy V et al. Cell Cycle 2015). The institute has first-hand access to the latest assays for high-throughput sequencing and single-cell profiling (Schmidl et al. Nat Methods 2015, Bock et al. Nat Biotechnol 2016, Datlinger et al. Nat Methods 2017). It also investigates the ethical and societal dimensions of rare diseases research. The institute is directed by Kaan Boztug, an experienced immunologist and rare diseases researcher. It is situated in a beautiful and well-designed building with state-of-the-art laboratories and technology platforms, located next to one of the world’s largest university hospitals in the heart of Vienna. The institute holds close ties with its renowned partners, namely the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, the Medical University of Vienna, and the Children’s Cancer Research Institute of the St. Anna Children’s Hospital. For more information please visit: www.rare-diseases.at
Initial appointments will be made for up to six years with tenure option, and the successful candidate will be offered a competitive salary and core research budget. Furthermore, the institute will provide support and mentoring to apply for additional external research funding at the Austrian and European level. Two of the four principal investigators at LBI-RUD hold prestigious grants by the European Research Council. LBI-RUD researchers are well-connected in global networks and will support young investigators in their effort to build up own new research collaborations in the field of rare and undiagnosed diseases.
Please submit a detailed CV including publication list, information on research interests, single most important achievement, a short proposal of planned research, and contact details of 3 referees as a single PDF file to firstname.lastname@example.org (reference code #PI/LBIRUD). Please also provide your timeline or earliest/latest starting date, respectively. Application deadline is 15 May 2017, or until the position is filled.
Commitment to Diversity
We believe that diversity and a multicultural work environment are clear advantages for successful research and are therefore committed to attract, develop, and advance the most talented individuals regardless of their gender, race, sexual orientation, religion, age, disability status or any other dimension of diversity. We are happy to provide help and assistance to all our employees, their spouses and family members in terms of visa and relocation procedures, dual-career and childcare services, and others.
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