Scientist, Immunology, New Venture Labs
An opportunity for a discovery biologist is available to join Moderna's early discovery group, New Venture Labs. New Venture Labs utilizes multidisciplinary approaches to understand protein structure, molecular signaling pathways, and dynamics of novel targets in preparation for their advancement into our drug discovery pipeline. Basic and applied research areas of interest include the immunopathogy of autoimmune disorders and the MOA of tolerance induction.
Specific projects will involve collaborative interactions in a multidisciplinary group and across diverse biology areas that target proteins and pathways in oncology, immunology, neuroscience and metabolism. This is a basic research position that requires critical thinking, flexibility, multitasking, and the ability to learn new techniques.
- Design and execution of well-controlled in vivo and in vitro experiments to demonstrate proof-of-concept in pre-clinical models of autoimmunity, and further develop deep mechanistic understanding of tolerogenesis.
- In-depth characterization of cellular and humoral immune responses in various mouse models of autoimmunity and humoral immunity.
- Develop, execute, and trouble-shoot assays, including in vitro differentiation of mouse/human dendritic and T cell subsets for in vitro assays, flow cytometry, ELISA, and microscopy.
- Manage collaborative relationships with project leads, key internal and external stakeholders, and the Moderna research leadership to resource and advance portfolio projects.
- Share and contribute scientific and technical know-how and experience with team members.
- Clearly analyze, communicate, and present scientific findings to senior management and teams to influence decision making from Immunology perspective.
- Ph.D. in immunology with 3 or more years spent overseeing the interaction of the immune system in the autoimmunity, immune oncology, and inflammatory diseases (in vivo models)
- Strong level of understanding and expertise in either one or more of the following: dendritic cell and Treg biology, immunology, nanoparticle biology, the complement system
- Demonstrated ability to design and execute new experimental approaches
- Publication of original scientific work in high-quality journals
- 3 years of independent research experience in the pharmaceutical or biotech industry will be a plus
- Excellent team spirit, communication and presentation skills